Exam Guide

Penicillin Allergy and an Amoxicillin Order

Foundations of Practice & Clinical Judgment · Question from the ATI PN Fundamentals 2023 Proctored Exam study set

Question: A nurse is reviewing a client with a UTI and a penicillin allergy. Which actions should the nurse take? (Select all that apply)
Clarify the prescription for amoxicillin with the provider

Correct answer: Clarify the prescription for amoxicillin with the provider

Why this is the answer

Amoxicillin is a penicillin-class antibiotic; a client with a penicillin allergy is at risk for a hypersensitivity reaction, so the nurse must clarify or question this order with the provider before administering it. (Additional actions, such as requesting an antiemetic or specific precautions, would depend on other client-specific findings not implied by the allergy itself.)

The bigger concept

The medication rights include checking allergies before every new drug, and knowing drug families is what makes the allergy check meaningful. Amoxicillin, ampicillin, and piperacillin are all penicillins; cephalosporins carry a smaller cross-reactivity risk. When an order conflicts with a documented allergy, the PN/VN holds the dose, clarifies with the provider, and documents the clarification — administering and 'watching closely' is never the right answer.

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